Modulation of tumor microenvironment

A - Human Necessities – 61 – K

Patent

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A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2682027

Compositions comprising CD80-targeted therapeutics and methods of using these compositions are provided for the treatment of a disease or disorder in which CD80-expressing cells or regulatory T cell function contribute to or exacerbate the associated pathology.

L'invention concerne des compositions comprenant des agents thérapeutiques ciblant le CD80 et des procédés d'utilisation de ces compositions pour le traitement d'une maladie ou d'un trouble dans lequel des cellules exprimant le CD80 ou une fonction de lymphocyte T régulatrice contribuent à la pathologie associée ou exacerbent celle-ci.

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