A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A61K 38/18 (2006.01) A61K 39/395 (2006.01) A61P 9/00 (2006.01) C07K 16/22 (2006.01)
Patent
CA 2368670
The present invention provides for a method of decreasing or inhibiting vascular permeability and/or plasma leakage in a mammal comprising administering to the mammal a TIE2 receptor activator. The invention also provides for a method of decreasing or inhibiting vascular permeability and/or plasma leakage in a mammal comprising administering to the mammal an Ang-2 inactivator such as an anti-Ang-2 neutralizing antibody.
La présente invention concerne une méthode de réduction ou d'inhibition de la perméabilité vasculaire et/ou des fuites de plasma chez un mammifère, consistant à lui administrer un activateur de récepteurs TIE2. L'invention concerne également un procédé de réduction ou d'inhibition de la perméabilité vasculaire et/ou de la fuite de plasma chez un mammifère, consistant à administrer à ce dernier un inactivateur de Ang-2 tel qu'un anticorps neutralisant anti Ang-2.
Mcdonald Donald
Suri Chitra
Thurston O. Gavin
Yancopoulos George D.
Osler Hoskin & Harcourt Llp
Regeneron Pharmaceuticals Inc.
The Regents Of The University Of California
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