Modulators of atp-binding cassette transporters

Details Modulators of atp-binding cassette transporters Modulators of atp-binding cassette transporters

A - Human Necessities

61

K

A61K 31/404 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 5/14 (2006.01) A61P 5/18 (2006.01) A61P 7/00 (2006.01) A61P 11/00 (2006.01) A61P 25/00 (2006.01) A61P 25/16 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2624683

The present invention relates to modulators of ATP-B inding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.

La présente invention concerne des modulateurs de transporteurs de cassette de liaison à l~ATP ('ABC') ou leurs fragments, y compris le Régulateur de conductance transmembranaire de la fibrose kystique ('CFTR'), des compositions et des méthodes qui en découlent. La présente invention concerne aussi des méthodes pour traiter des maladies impliquant des transporteurs ABC en utilisant de tels modulateurs.

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