Modulators of atp-binding cassette transporters

Details Modulators of atp-binding cassette transporters Modulators of atp-binding cassette transporters

C - Chemistry, Metallurgy

07

D

C07D 277/82 (2006.01) A61K 31/426 (2006.01) A61P 43/00 (2006.01) C07D 263/48 (2006.01) C07D 277/46 (2006.01) C07D 417/04 (2006.01) C07D 417/06 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2537841

The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including CF Transmembrane Regulator ("CFTR"), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.

L'invention concerne des modulateurs de transporteurs à cassette de liaison à l'ATP ("ABC") ou des fragments de ceux-ci, comprenant un régulateur transmembranaire de CF ("CFTR"). L'invention porte sur les compositions desdits modulateurs et sur des procédés dans lesquels ils sont utilisés. Elle se rapporte également à des méthodes de traitement de maladies médiées par les transporteurs ABC au moyen de ces modulateurs.

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