Modulators of atp-binding cassette transporters

Details Modulators of atp-binding cassette transporters Modulators of atp-binding cassette transporters

C - Chemistry, Metallurgy

07

D

C07D 239/42 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/04 (2006.01) C07D 409/14 (2006.01) C07D 491/10 (2006.01)

Patent

CA 2609392

4-amido-pyrimidine compounds, derivatives and compositions thereof, and synthetic methods described herein are useful for modulating ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"). The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.

L'invention concerne des composés de 4-amido-pyrimidine, des dérivés et des compositions de ceux-ci, ainsi que des méthodes de synthèse, utilisés dans la modulation des transporteurs de cassette de liaison à l'ATP ("ABC") ou des fragments de ceux-ci, y compris le régulateur de conductance transmembranaire de la fibrose cystique ("CFTR"). La présente invention concerne également des méthodes de traitement des maladies médiées par les transporteurs ABC à l'aide desdits modulateurs.

Affiliated with

Also associated with

Rating

Modulators of atp-binding cassette transporters does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Modulators of atp-binding cassette transporters, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Modulators of atp-binding cassette transporters will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1983981