Modulators of atp-binding cassette transporters

Details Modulators of atp-binding cassette transporters Modulators of atp-binding cassette transporters

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/47 (2006.01) A61K 31/4709 (2006.01) A61P 25/00 (2006.01) A61P 31/00 (2006.01) C07C 215/76 (2006.01) C07D 209/08 (2006.01) C07D 209/12 (2006.01) C07D 209/14 (2006.01) C07D 209/18 (2006.01) C07D 215/56 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2571949

The present invention relates to modulators of ATP-Binding Cassette (~ABC~) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.

La présente invention a trait à des modulateurs de transporteurs de cassette de liaison à l'ATP (la voie ABC) ou des fragments de ceux-ci, comprenant le régulateur de conductance transmembranaire de la fibrose cystique, des compositions de ceux-ci, et des procédés réalisés à l'aide de ceux-ci. La présente invention a également trait à des procédés de traitement de maladies causées par l'intermédiaire de transporteurs de la voie ABC mettant en oeuvre de tels modulateurs.

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