Modulators of carnitine octanoyltransferase in the treatment...

Details Modulators of carnitine octanoyltransferase in the treatment... Modulators of carnitine octanoyltransferase in the treatment...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2722072

The invention relates to an in vitro or in vivo method for screening for candidate compounds for the preventive or curative treatment of acne, of seborrhoeic dermatitis or of skin disorders associated with hyperseborrhoea, comprising the determi-nation of the ability of a compound to modulate the expression or the activity of carnitine octanoyltransferase (CROT), and also to the use of modulators of the expression or of the activity of this enzyme, for the treatment of acne, of seborrhoeic dermatitis or of skin disorders associated with hyperseborrhoea. The invention also relates to methods for the in vitro diagnosis of or in vitro prognosis for these pathologies.

L'invention concerne un procédé in vitro ou in vivo pour cribler des composés candidats destinés au traitement préventif ou curatif de l'acné, de la dermatite séborrhéique ou d'affections cutanées associées à une hyperséborrhée. Ce procédé consiste à déterminer l'aptitude d'un composé à moduler l'expression ou l'activité de la carnitine octanoyltransférase (CROT). L'invention concerne également l'utilisation de modulateurs de l'expression ou de l'activité de ladite enzyme, pour traiter l'acné, la dermatite séborrhéique ou des affections cutanées associées à une hyperséborrhée. L'invention concerne encore des procédés de diagnostic in vitro ou de pronostic in vitro de ces pathologies.

Affiliated with

Also associated with

Rating

Modulators of carnitine octanoyltransferase in the treatment... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Modulators of carnitine octanoyltransferase in the treatment..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Modulators of carnitine octanoyltransferase in the treatment... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1712406