Modulators of cxcr7

Details Modulators of cxcr7 Modulators of cxcr7

C - Chemistry, Metallurgy

07

D

C07D 417/14 (2006.01) A61K 31/551 (2006.01) A61K 49/00 (2006.01) A61K 51/04 (2006.01) C07D 401/10 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2742515

Compounds having formula (I) or pharmaceutically acceptable salts, hydrates or N-oxides thereof are provided and are useful for binding to CXCR7, and treating diseases that are dependent, at least in part, on CXCR7 activity. Accordingly, the present invention provides in further aspects, compositions containing one or more of the above-noted compounds in admixture with a pharmaceutically acceptable excipient.

La présente invention concerne des composés de formule (I) ou leurs sels pharmaceutiquement acceptables, hydrates ou N-oxydes qui sont utiles pour la liaison au CXCR7 et au traitement de maladies qui sont dépendantes, au moins en partie, de lactivité du CXCR7. En conséquence, la présente invention a pour objet dans dautres aspects, des compositions contenant un ou plusieurs des composés notés ci-dessus en mélange avec un excipient pharmaceutiquement acceptable.

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