Modulators of cysteine protease

Details Modulators of cysteine protease Modulators of cysteine protease

A - Human Necessities

61

K

A61K 31/12 (2006.01) A61K 31/00 (2006.01) A61K 31/11 (2006.01) A61K 31/121 (2006.01) A61K 31/122 (2006.01) A61K 31/165 (2006.01) A61K 31/166 (2006.01) A61K 31/216 (2006.01) A61K 31/22 (2006.01) A61K 31/366 (2006.01) A61K 31/415 (2006.01) A61K 31/4152 (2006.01) A61K 31/42 (2006.01) A61K 31/423 (2006.01) A61K 31/44 (2006.01) A61K 31/4415 (2006.01) A61K 31/60 (2006.01)

Patent

CA 2313212

The present invention concerns novel mediators of the activity of picornavirus 3C protease and the modulation of the activity of other similar proteins. The modulators may be used in pharmaceutical compositions either for inhibition of 3C protease (for example in viral infections) or for the enhancement of the activity of proteins similar to the 3C protease such as Apopain (for induction of apoptosis).

La présente invention concerne de nouveaux médiateurs de l'activité de la picornavirus protéase 3C et la modulation de l'activité d'autres protéines similaires. Ces modulateurs peuvent être utilisés dans des compositions pharmaceutiques, soit pour l'inhibition de la protéase 3C (par exemple en cas d'infection virale), soit pour la stimulation de l'activité de protéines similaires à la protéase 3C, telles que l'apopaïne (pour l'induction de l'apoptose).

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