C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/12 (2006.01) A61K 31/4709 (2006.01) A61P 11/00 (2006.01) C07D 451/02 (2006.01) C12Q 1/02 (2006.01)
Patent
CA 2741718
The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator ("CFTR"), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR. (1); or pharmaceutically acceptable salts thereof, wherein: ring A is selected from:
La présente invention concerne des modulateurs de régulateur de conductance transmembranaire de mucoviscidose (« CFTR »), des compositions de ceux-ci, et des procédés avec ceux-ci. La présente invention concerne en outre des procédés de traitement de maladies utilisant des modulateurs de CFTR.
Binch Hayley
Botfield Martyn
Fanning Lev T.d.
Grootenhuis Peter D.j.
Hurley Dennis
Smart & Biggar
Vertex Pharmaceuticals Incorporated
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