C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 495/04 (2006.01) A61K 31/407 (2006.01) A61P 11/00 (2006.01)
Patent
CA 2688004
The present invention relates to modulators of ATP-B inding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
La présente invention concerne des modulateurs de transporteurs de cassette de liaison d'ATP-B (<= ABC >=) ou des fragments de ceux-ci, y compris le régulateur de conductance transmembranaire de fibrose cystique, des compositions de ceux-ci et des procédés pour ceux-ci. La présente invention concerne également des procédés de traitement de maladies véhiculées par transporteur d'ABC utilisant de tels modulateurs.
Binch Hayley
Grootenhuis Peter
Hadida Ruah Sara
Zhou Jinglan
Smart & Biggar
Vertex Pharmaceuticals Incorporated
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