Modulators of metabolism and the treatment of disorders...

Details Modulators of metabolism and the treatment of disorders... Modulators of metabolism and the treatment of disorders...

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/506 (2006.01) A61P 5/50 (2006.01)

Patent

CA 2619093

The present invention relates to 4-[5-methyl-6-(2-methyl-pyridin-3-yloxy)- pyrimidin-4-yloxy]-piperidine-1-carboxylic acid isopropyl ester, pharmaceutically acceptable salts, solvates and hydrates thereof that are modulators of glucose metabolism. Accordingly, compounds of the present invention are useful in the treatment of metabolic-related disorders and complications thereof, such as, diabetes and obesity.

La présente invention concerne un ester isopropylique d~acide de 4-[5-méthyl-6-(2-méthyl-pyridin-3-yloxy)-pyrimidin-4-yloxy]-piperidinepipéridine-1-carboxylique, des hydrates, solvates et sels pharmaceutiquement acceptables de celui-ci qui sont des modulateurs du métabolisme du glucose. En conséquence, des composés de la présente invention sont utiles dans le traitement de troubles métaboliques et de complications de ceux-ci, tels que des diabètes et l~obésité.

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