A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4245 (2006.01) A61P 15/16 (2006.01) A61P 15/18 (2006.01)
Patent
CA 2612387
The invention provides novel compositions and compounds that inhibit CatSper channel activity, that preferentially inhibits sperm hyperactivity over sperm motility, or both. The compounds of the invention are useful as contraceptive agents that may be adminstered to males, females, or concurrently to both sexual partners. The invention further provides methods of conducting drug discovery business and of conducting a reproductive medicine business. The invention also provides methods of identifying compounds that modulate sperm hypermotility.
La présente invention concerne de nouvelles compositions et de nouveaux composés qui inhibent l'activité de la voie catsper, qui inhibe de préférence l'hyperactivité du sperme plutôt que l'hypermotilité du sperme ou les deux. Les composés de l'invention conviennent comme agents contraceptifs qui peuvent être administrés à des hommes, des femmes ou simultanément aux deux partenaires sexuels. Cette invention concerne aussi des procédés permettant de conduire la recherche de médicaments et de conduire de travail de la médecine reproductive. Cette invention concerne aussi des procédés identification de composés qui modulent l'hypermotilité du sperme.
Chong Jayhong A.
Moran Magdalene M.
Borden Ladner Gervais Llp
Hydra Biosciences Inc.
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