Modulators of the glucocorticoid receptor

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 39/23 (2006.01) A61K 31/05 (2006.01) A61K 31/33 (2006.01) A61P 5/46 (2006.01) C07C 35/42 (2006.01) C07C 39/17 (2006.01) C07C 39/42 (2006.01) C07C 43/23 (2006.01) C07C 49/747 (2006.01) C07C 49/755 (2006.01) C07C 49/83 (2006.01) C07C 59/72 (2006.01) C07C 205/57 (2006.01) C07D 211/40 (2006.01) C07D 213/30 (2006.01) C07D 213/40 (2006.01) C07D 241/52 (2006.01) C07D 257/04 (2006.01) C07D 265/28 (2006.01) C07D 271/06 (2006.01) C07D 277/24 (2006.01) C07D 295/092 (2006.01) C07D 295/185 (2006.01) C07D 413/06 (20

Patent

CA 2491994

The present invention provides compounds of the formula wherein A is of the formula and X, Y, n, R1-R25 are as described in the specification which are modulators of the glucocorticoid receptor and are thus useful for the treatment of animals requiring glucocorticoid receptor ágonist.therapy. Glucocorticoid-receptor modulators are useful in the treatment of certain inflammatory conditions.

L'invention porte sur composés de formule (I) dans laquelle: A est la formule (II), (III) où (IV) et X, Y, n, R?1¿-R?25¿ sont tels que définis dans la spécification. Lesdits composés sont des modulateurs du récepteur glucocorticoïde, et s'avèrent de ce fait utiles pour le traitement d'animaux requérant une thérapie par un agoniste du récepteur glucocorticoïde, et pour le traitement de certains troubles inflammatoires.

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