Molecular analytical release tags and their use in chemical...

C - Chemistry – Metallurgy – 07 – D

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150/11, 167/44,

C07D 207/46 (2006.01) C07K 5/06 (2006.01) G01N 33/532 (2006.01) G01N 33/58 (2006.01) G01N 33/78 (2006.01)

Patent

CA 1246058

ABSTRACT A new class of chemical reagents called release tags which comprise signal, release and reactivity groups is disclosed and a release tag involving a pentafluorobenzoyl signal group, a methionylamide release group, and an active ester reactivity group is used to analyze the hormone, thyroxine, in serum, involving quantitation of the released signal group by gas chromatography with electron capture detection.

420574

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