Molecular antigen array presenting amyloid beta

Details Molecular antigen array presenting amyloid beta Molecular antigen array presenting amyloid beta

A - Human Necessities

61

K

A61K 39/385 (2006.01) A61K 39/00 (2006.01) A61K 39/35 (2006.01) A61K 47/48 (2006.01) A61P 25/28 (2006.01) C07K 14/02 (2006.01) C07K 14/08 (2006.01) C07K 14/245 (2006.01) C07K 14/47 (2006.01) C07K 14/52 (2006.01) C07K 14/54 (2006.01) C07K 16/00 (2006.01) C07K 16/08 (2006.01) C07K 16/22 (2006.01) C07K 16/28 (2006.01) C07K 16/40 (2006.01) C07K 16/42 (2006.01) A61K 38/11 (2006.01)

Patent

CA 2433862

The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in the production of vaccines for the treatment of infectious diseases, the treatment of allergies and as a pharmaccine to prevent or cure cancer and to efficiently induce self-specific immune responses, in particular antibody responses.

L'invention concerne les domaines de la biologie moléculaire, de la virologie, de l'immunologie et de la médecine. Elle concerne une composition comprenant un antigène répétitif et ordonné ou un jeu ordonné de déterminant antigénique. Elle concerne aussi un processus de production d'un antigène ou d'un déterminant antigénique dans un jeu ordonné et répétitif. On utilise cet antigène ou ce déterminant antigénique répétitif et ordonné dans la production de vaccins destinés au traitement de maladies infectieuses, d'allergies et en tant que "pharmaccins" (vaccins thérapeutiques) aux fins de prévention ou de guérison de cancer et d'induction efficace de réponses immunes auto-spécifiques, en particulier des réponses d'anticorps.

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