C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/00 (2006.01) C07C 323/60 (2006.01) C07K 16/42 (2006.01) C07K 16/44 (2006.01) G01N 33/532 (2006.01)
Patent
CA 2631005
A method is disclosed for making a conjugate of two molecules using a hydrazide thiol linker. In a particular working embodiment, an Fc-specifÊc antibody- enzyme conjugate is made using the method and demonstrated to provide exceptional staining sensitivity and specificity in immunohistochemical and in situ hybridization assays.
La présente invention concerne un procédé pour préparer un conjugué de deux molécules en utilisant un groupe de liaison hydrazide-thiol. Dans un mode de réalisation pratique particulier, un conjugué anticorps spécifique Fc-enzyme est préparé en utilisant le procédé et il présente une sensibilité de coloration et une spécificité exceptionnelles en immunohistochimie et dans des dosages d'hybridation in situ.
Ashworth-Sharpe Julia
Bieniarz Christopher
Kernag Casey A.
Kosmeder Jerome W.
Lefever Mark
Mbm Intellectual Property Law Llp
Ventana Medical Systems Inc.
LandOfFree
Molecular conjugate does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Molecular conjugate, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Molecular conjugate will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1836036