Molecular/genetic aberrations in surgical margins of...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C40B 30/04 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2617755

The present invention relates to the detection of field cancerization by detection of aberrations in tumor target genes at the margins of resected tumors, and the use of such information to predict survival in cancer patients. Methods for treatment of cancer based thereon also are provided.

La présente invention traite de la détection de la cancérisation sur champ par le biais de la détection d~aberrations dans les gènes cibles de la tumeur, dans les marges de tumeurs réséquées, et de l~utilisation de ces informations pour prévoir la survie des patients atteints de cancer. L'invention concerne également des méthodes de traitement du cancer associées.

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