C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/70 (2006.01)
Patent
CA 2663164
The present invention relates to compositions and methods that allow the manipulation of the catalytic activity of multi-component nucleic acid complexes. Further, the invention provides methods which use these compositions and methods to create molecular sensors, molecular switches, and/or modulators or propagators of autocatalytic self-replicating cascades and other iterative processes. More particularly, the invention relates to compositions allowing self-assembly of active and inactive multicomponent nucleic acid complexes, methods of making such compositions, and methods for use.
La présente invention concerne des compositions et des procédés permettant d'agir sur l'activité catalytique de complexes d'acides nucléiques multicomposants. En outre, l'invention concerne des procédés utilisant ces compositions et ces procédés en vue de créer des détecteurs moléculaires, des commutateurs moléculaires et/ou des modulateurs ou des propagateurs de cascades autoréplicatrices et autocatalytiques, ainsi que d'autres processus itératifs. L'invention concerne, plus particulièrement, des compositions permettant un auto-assemblage de complexes d'acides nucléiques multicomposants actifs et inactifs, des procédés de production desdites compositions et des procédés d'utilisation de celles-ci.
Birkett Donald John
Doan Tram Bich
Mokany Elisa
Reid Christopher Roland
Todd Alison Velyian
Johnson & Johnson Research Pty Limited
Smart & Biggar
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