Molecular torches

Details Molecular torches Molecular torches

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2333253

The present invention features "molecular torches" and the use of molecular torches for detecting the presence of a target nucleic acid sequence. Molecular torches contain a target binding domain, a target closing do-main, and a joining region. The target binding domain is biased towards the target sequence such that the target binding domain forms a more stable hybrid with the target sequence than with the target closing domain under the same hybridization conditions. The joining region facilitates the formation or maintenance of a closed torch.

Dans la présente invention, on divulgue des torches moléculaires et leur utilisation pour détecter la présence d'une séquence d'acides nucléiques cible. Les torches moléculaires contiennent un domaine de liaison cible, un domaine de fermeture cible et une zone d'assemblage. Le domaine de liaison cible est décalé vers la séquence cible de telle sorte que le domaine de liaison cible forme un hybride plus stable avec la séquence cible qu'avec le domaine de fermeture cible dans les mêmes conditions d'hybridation. La zone d'assemblage facilite la formation ou la maintenance d'une torche fermée.

Affiliated with

Also associated with

Rating

Molecular torches does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Molecular torches, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Molecular torches will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2009037