Moleculary cloned acquired immunodeficiency syndrome...

C - Chemistry – Metallurgy – 12 – N

Patent

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530/13, 195/1.22

C12N 15/62 (2006.01) A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61K 39/21 (2006.01) C07K 14/035 (2006.01) C07K 14/15 (2006.01) C07K 14/16 (2006.01) C07K 14/245 (2006.01) C07K 14/47 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01) C12N 15/31 (2006.01) C12N 15/85 (2006.01) C12P 21/00 (2006.01) C12Q 1/48 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1341476

Diagnostic product and vaccine for Acquired Immuno-deficiency Syndrome (AIDS) and methods for making and using same, wherein viral polypeptide sequences from an AIDS associated retrovirus are expressed directly or as a fusion polypeptide in a prokaryotic or mammalian cell expression host to produce a diagnostic product which specifically binds complementary antibody produced by individuals afflicted with AIDS or a vaccine against AIDS which confers resistance to infection by AIDS associated retrovirus. the reverse transcriptase of an AIDS associated retrovirus is used separately or in a whole cell assay to identify compounds which selectively inhibit retroviral reverse transcriptase.

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