C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 1/113 (2006.01) A61K 38/17 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2454768
We disclose a method of stabilising the native state of a polypeptide, the method comprising exposing the polypeptide to a stabilising molecule capable of binding to the polypeptide at a site which at least partially overlaps a functional site in its native state.
L'invention concerne un procédé de stabilisation de l'état natif d'un polypeptide, consistant à exposer le polypeptide à une molécule de stabilisation capable de se lier au polypeptide en un site qui chevauche au moins partiellement un site fonctionnel à l'état natif.
Fersht Alan
Friedler Assaf
Mbm Intellectual Property Law Llp
Medical Research Council
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