Molecules and methods for inhibiting shedding of kim-1

Details Molecules and methods for inhibiting shedding of kim-1 Molecules and methods for inhibiting shedding of kim-1

C - Chemistry, Metallurgy

07

K

C07K 16/00 (2006.01) A61K 38/55 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) C12N 5/16 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2448427

Disclosed are antibodies that inhibit proteolytic release of soluble KIM-1 polypeptide from KIM-1 expressing cells. Also disclosed are methods of using the antibodies to inhibit shedding of the KIM-1 polypeptide.

Cette invention concerne des anticorps qui inhibent la libération protéolytique du polypeptide KIM-1 soluble à partir de cellules exprimant KIM-1. Sont également décrites des méthodes d'utilisation des anticorps dans le but d'empêcher la libération du 'polypeptide KIM-1.

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