C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/00 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2442705
The present invention provides purified human polynucleotides for diagnostics and therapeutics (dithp). Also encompassed are the polypeptides (DITHP) encoded by dithp. The invention also provides for the use of dithp, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing dithp for the expression of DITHP. The invention additionally provides for the use of isolated and purified DITHP to induce antibodies and to screen libraries of compounds and the use of anti-DITHP antibodies in diagnostic assays. Also provided are microarrays containing dithp and methods of use.
L'invention concerne des polynucléotides humains purifiés utilisés à des fins diagnostiques et thérapeutiques (dithp). L'invention concerne par ailleurs des polypeptides (DITHP) codés par dithp, l'utilisation de dithp, ou de compléments, d'oligonucléotides, ou de fragments de celle-ci dans des méthodes diagnostiques. De plus, l'invention concerne des vecteurs et des cellules hôtes contenant dithp pour l'expression de DITHP. L'invention concerne en outre l'utilisation de DITHP isolée et purifiée pour induire des anticorps et cribler des banques de composés ainsi que l'utilisation des anticorps anti-DITHP dans des méthodes d'agnostiques. L'invention concerne enfin des micro-réseaux contenant dithp et des méthodes d'utilisation correspondantes.
Amshey Stefan R.
Chen Alice J.
Chinn Joyce
Daffo Abel
Dahl Christopher R.
Amshey Stefan R.
Chen Alice J.
Chinn Joyce
Daffo Abel
Dahl Christopher R.
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