A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/167 (2006.01) A61K 31/18 (2006.01) A61K 31/33 (2006.01) A61K 31/343 (2006.01) A61K 31/351 (2006.01) A61K 31/4015 (2006.01) A61K 31/4025 (2006.01) A61K 31/4035 (2006.01) A61K 31/404 (2006.01) A61K 31/41 (2006.01) A61K 31/4155 (2006.01) A61K 31/4162 (2006.01) A61K 31/4178 (2006.01) A61K 31/4196 (2006.01) A61K 31/427 (2006.01) A61K 31/435 (2006.01) A61K 31/445 (2006.01) A61K 31/451 (2006.01) A61K 31/4525 (2006.01) A61K 31/4704 (2006.01) A61K 31/495 (2006.01) A61K 31/502 (2006.01) A61K 31/506 (2006.01)
Patent
CA 2720908
The present invention relates to the C-13 molecule (methyl 2-{5-[(3-benzyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-2-furyl}benzoate) and to organic molecules functionally equivalent to the C-13 molecule, capable of inhibiting the binding of an antibody or antibody fragment with the human Syk protein tyrosine kinase, to the use of these molecules for the production of medicaments for the prevention or treatment of diseases dependent on metabolic pathways involving Syk, and also to a method for identifying such molecules.
La présente invention est relative la molécule C-13 (méthyl 2-{5-[(3-benzyl-4- oxo-2-thioxo-1,3- thiazolidin-5- ylidene)méthyl]-2-furyl}benzoate) et à des molécules organiques équivalentes sur le plan fonctionnel à la molécule C-13, capables d'inhiber la liaison d'un anticorps ou fragment d'anticorps avec la protéine tyrosine kinase Syk humaine, à l'utilisation de ces molécules pour la fabrication de médicaments pour la prévention ou le traitement de pathologies dépendantes de voies métaboliques impliquant Syk, ainsi qu'à un procédé d'identification de telles molécules.
Dariavach Piona
Martineau Pierre Emile Ulysse
Villoutreix Bruno
Centre National de La Recherche Scientifique
Robic
LandOfFree
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