C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 38/04 (2006.01) C07K 14/47 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2407945
The invention relates to methods for identifying compounds that modulate ubiquitin-dependent proteolysis, and compounds identified using the methods. The invention also relates to a novel peptide motif referred to as the "CPD motif", molecules derived from the CPD motif, and uses of the CPD motif and molecules.
Cette invention se rapporte à des procédés permettant d'identifier des composés qui modulent la protéolyse dépendant de l'ubiquitine, ainsi qu'à des composés identifiés à l'aide de ces procédés. Cette invention concerne également un nouveau motif peptidique appelé "motif CPD", des molécules tirées de ce motif CPD, et des utilisations de ce motif CPD et de ces molécules.
Nash Piers
Pawson Tony
Tang Xiaojing
Tyers Mike
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Mount Sinai Hospital
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