Molecules with antibody combining sites that induce asymmetry

C - Chemistry – Metallurgy – 12 – P

Patent

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C12P 21/08 (2006.01) C07B 53/00 (2006.01) C07K 16/00 (2006.01) C12N 5/16 (2006.01) C12N 9/00 (2006.01) C12N 9/16 (2006.01)

Patent

CA 2118707

2118707 9305146 PCTABS00020 Monoclonal antibodies or paratope-containing portions thereof are disclosed that immunoreact with a meso diester substrate ligand and catalytically hydrolyze a single predetermined ester bond to form one of a pair of enantiomers. Methods of making and using the same are also disclosed.

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