G - Physics – 06 – F
Patent
G - Physics
06
F
G06F 19/00 (2011.01) G01N 33/48 (2006.01) G06F 17/18 (2006.01)
Patent
CA 2579187
Clinical data that are measured at a plurality of sequential time points are interpreted by monitoring the Z-value of the clinical data. The Z-value of the measured data is calculated at each of the time points. The calculated Z- values are plotted and compared against a pre-selected Z-value, which may be Z = 5, in one exemplary embodiment. The clinical data are determined to have undergone a statistically significant change, compared to a baseline value BV of the data, when the calculated Z-value for the measured data is greater than or substantially equal to the pre-selected Z-value. In this way, signal detection from biomarker data may be enhanced. Also, the toxicity level of drugs that are tested in clinical trials may be determined in a more reliable fashion.
Covance Inc.
G. Ronald Bell & Associates
LandOfFree
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