Mono (2-ammonium-2-hydroxymethyl-1,3-propanediol)...

Details Mono (2-ammonium-2-hydroxymethyl-1,3-propanediol)... Mono (2-ammonium-2-hydroxymethyl-1,3-propanediol)...

C - Chemistry, Metallurgy

07

F

167/243, 260/369

C07F 9/655 (2006.01) A61K 31/665 (2006.01)

Patent

CA 2021809

MONO (2-AMMONIUM-2-HYDROXYMETHYL-1,3-PROPANEDIOL)(2R,CIS)-1,2-EP- OXIPROPYL-PHOSPHONATE WITH IMPROVED CHRARCTERISTICS OF STABILITY AND PROCESSING A b s t r a c t A proccss is described for the preparation of mono (2-ammonium-2- hydroxymethyl-1,3-propanediol)(2R,cis)-1,2-epoxyplopyl-phosphonate with improved characteristics of stability, of processing for the preparation of pharmaceutical forms and of stability of the pharmaceutical forms that contain it.

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