Mono- and disaccharides for the treatment of nitric oxide...

Details Mono- and disaccharides for the treatment of nitric oxide... Mono- and disaccharides for the treatment of nitric oxide...

A - Human Necessities

61

K

A61K 31/70 (2006.01) A61P 9/10 (2006.01) C07H 13/06 (2006.01) C07H 15/04 (2006.01)

Patent

CA 2403075

Methods for treating diseases or conditions modulated or ameliorated by nitric oxide, particularly ischemia and reperfusion injury, are provided, using glycolipids structurally related to monophosphoryl lipid A but with notable reduction in proinflammatory and pyrogenic activity.

L'invention concerne des méthodes de traitement de maladies ou d'états modulés ou améliorés par l'oxyde nitrique, particulièrement l'ischémie ou les lésions de reperfusion, au moyen de glycolipides relatifs, sur le plan de la structure, au lipide A monophosphoryle mais présentant une réduction notable de l'activité proinflammatoire et pyrogénique.

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