Monoclonal and chimeric antibodies specific for human tumor...

Details Monoclonal and chimeric antibodies specific for human tumor... Monoclonal and chimeric antibodies specific for human tumor...

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 16/24 (2006.01) C07K 16/46 (2006.01)

Patent

CA 2736076

Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-.alpha.(TNF.alpha.) and are useful in vivo diagnosis and therapy of a number of TNF.alpha.-mediated pathologies and conditions, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of the anti-TNF antibody, or fragment, region or derivative thereof, in immunoassays and immunotherapeutic approaches are provided.

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