C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61M 1/38 (2006.01) C07K 1/22 (2006.01) C07K 5/10 (2006.01) C07K 14/525 (2006.01) C07K 16/24 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2106299
Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-.alpha. (TNF.alpha.) and are useful in vivo diagnosis and therapy of a number of TN Fu-mediated pathologies and conditions, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of the anti-TNF antibody, or fragment, region or derivative thereof, in immunoassays and immunotherapeutic approaches are provided,
Daddona Peter E.
Ghrayeb John
Knight David M.
Le Junming
Siegel Scott A.
Centocor Inc.
Gowling Lafleur Henderson Llp
New York University
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