C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/18 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/42 (2006.01) C12N 15/13 (2006.01) C12N 15/63 (2006.01) C12P 21/08 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2163868
Disclosed is an anti-idiotypic antibody which reacts with an anti-CA125 antibody and competes with CA125 in its binding to said anti-CA125 antibody. Furthermore, fragments of said anti-idiotypic antibody are disclosed which have essentially the same binding specificity. Additionally, the invention relates to cell lines, particularly to hybridoma 3D5 (DSM ACC2120), producing said anti-idiotypic antibodies. Also disclosed are pharmaceutical compositions containing said anti--idiotypic antibodies and specific uses of these antibodies.
Anticorps antiidiotypiques réagissant avec un anticorps anti-CA125 et entrant en compétition avec CA125 pour la liaison audit anticorps anti-CA125. L'invention se rapporte en outre à des fragments de cet anticorps antiidiotypique qui présentent la même spécificité de liaison, ainsi qu'à des lignées cellulaires, en particulier l'hybridome 3D5 (DSM ACC2120), qui produisent ces anticorps antiidiotypiques. L'invention se rapporte également à des compositions pharmaceutiques contenant de tels anticorps antiidiotypiques et à leurs utilisations spécifiques.
Schlebusch Harald
Wagner Uwe
Mbm Intellectual Property Law Llp
Schlebusch Harald
Wagner Uwe
LandOfFree
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