Monoclonal anti-igm antibodies, their production and use,...

C - Chemistry – Metallurgy – 12 – P

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C12P 21/08 (2006.01) A61K 47/48 (2006.01) C07K 16/42 (2006.01) C07K 16/46 (2006.01) C12N 5/18 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2079901

2079901 9117257 PCTABS00008 A principal aspect of the invention concerns rat monoclonal antibodies that: (a) bind selectively to IgM sub-type antibodies; (b) are IgGs; (c) do not bind to IgG1 or IgG2 sub-type. The preferred embodiment of these antibodies is one designated 2G10, and functional equivalents thereof.

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