Monoclonal antibiodies for selective immunological...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/12 (2006.01) C07K 16/18 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2155793

The present invention relates to monoclonal antibodies for the selective immunological determination of high molecular weight forms of laminin in body fluids, to a process for preparing these antibodies, and to their use for diagnosing diseases. The antibodies according to the invention preferably bind to intact, native laminin, in particular to the structures of the laminin P1 domain of laminin which are folded in a native manner.

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