Monoclonal antibodies

Details Monoclonal antibodies Monoclonal antibodies

C - Chemistry, Metallurgy

07

K

167/129, 167/139

C07K 16/18 (2006.01) A61K 39/00 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) C07K 5/04 (2006.01) C07K 7/04 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2003211

ABSTRACT Monoclonal antibodies which specifically bind to the amino acid sequence ALA PRO ASP THR ARG of the repeat sequence of human polymorphic epithelial mucin. The antibodies can be used to detect mucin in biological fluids, and thus can be used to detect adenocarcinomas which are characterised by high levels of mucin production. Peptides which correspond in amino acid sequence to the epitope recognised by the monoclonal antibodies may be used as therapeutic agents in vaccines for the treatment of adenocarcinoma.

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