Monoclonal antibodies against angptl3

Details Monoclonal antibodies against angptl3 Monoclonal antibodies against angptl3

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01) A61K 39/395 (2006.01) A61P 3/06 (2006.01) C07K 16/22 (2006.01) C07K 16/46 (2006.01)

Patent

CA 2672049

Monoclonal antibodies that specifically bind to ANGPTL3 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL3 are provided. Methods of treating a disorder of lipid metabolism using neutralizing monoclonal antibodies are provided.

L'invention concerne des anticorps monoclonaux qui se lient spécifiquement à ANGPTL3. L'invention concerne également des anticorps monoclonaux qui neutralisent au moins une activité de l'ANGPTL3. L'invention concerne enfin des méthodes de traitement d'un trouble du métabolisme lipidique faisant appel à des anticorps monoclonaux neutralisants.

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