C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/30 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C12N 5/12 (2006.01)
Patent
CA 2687206
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLDl 8, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, cancer of the gallbladder, and the metastases thereof.
La présente invention propose des anticorps qui s'utilisent en tant que produits thérapeutiques pour traiter et/ou prévenir des maladies associées à des cellules exprimant CLD18, dont des maladies liées à une tumeur telles que le cancer gastrique, le cancer de l'AEsophage, le cancer du pancréas, le cancer des poumons, le cancer des ovaires, le cancer du côlon, le cancer hépatique, le cancer de la tête et du cou, le cancer de la vésicule biliaire et leurs métastases.
Brandenburg Gunda
Sahin Ugur
Tuereci Oezlem
Usener Dirk
Ganymed Pharmaceuticals Ag
Gowling Lafleur Henderson Llp
Johannes Gutenberg-Universitaet Mainz
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