C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/30 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C12N 5/12 (2006.01)
Patent
CA 2628126
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLDl 8, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.
La présente invention concerne des anticorps à utiliser comme thérapeutique pour traiter et/ou prévenir des maladies associées à des cellules qui expriment CLDl 8, y compris des maladies tumorales apparentées telles que cancer gastrique, cancer oesophagien, cancer pancréatique, cancer du poumon, cancer ovarien, cancer du côlon, cancer hépatique, cancer de la tête et du cou et cancer de la vésicule biliaire.
Brandenburg Gunda
Fritz Stefan
Geppert Harald-Gerhard
Sahin Ugur
Schroeder Anja Kristina
Ganymed Pharmaceuticals Ag
Gowling Lafleur Henderson Llp
Johannes Gutenberg-Universitaet Mainz Vertreten Durch Den Praesidenten
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