Monoclonal antibodies against the interferon receptor, with...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/28 (2006.01) A61K 38/00 (2006.01) A61K 39/395 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07K 14/715 (2006.01) C12N 5/12 (2006.01) C12N 5/16 (2006.01) C12P 21/08 (2006.01) C12Q 1/18 (2006.01) C12Q 1/70 (2006.01) G01N 33/566 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2133106

The invention relates to a monoclonal antibody directed against the human interferon class I receptor (IFN-R) characterized by the following properties: it recognizes the extracellular domain of the human IFN-R, and it has a neutralizing capacity against the biological properties of the human type I-IFN. It further concerns their use for the diagnosis.

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