Monoclonal antibodies and hybridoma cells, to humain reinin:...

Details Monoclonal antibodies and hybridoma cells, to humain reinin:... Monoclonal antibodies and hybridoma cells, to humain reinin:...

C - Chemistry, Metallurgy

12

P

195/1.111

C12P 21/00 (2006.01) C07K 16/40 (2006.01) C12P 5/00 (2006.01) C12P 15/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1277261

Novel monoclonal antibodies and hybridoma cells, processes for their preparation and their applications Abstract The invention relates to novel monoclonal antibodies having a high affinity for human renin, derivatives thereof, processes for the preparation of these antibodies and their derivatives, hybridoma cell lines that produce these antibodies, and to processes for the preparation of said hybridoma cells lines. The monoclonal antibodies according to the invention and their derivatives can be used for the qualitative and quantitative determination of human renin and struc- turally similar renin, for the purification of human renin and structurally similar renin and for the treatment of high blood pressure and cardiac insufficiency.

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