Monoclonal antibodies and single chain antibody fragments...

Details Monoclonal antibodies and single chain antibody fragments... Monoclonal antibodies and single chain antibody fragments...

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 47/48 (2006.01) C07K 16/30 (2006.01)

Patent

CA 2609682

Isolated monoclonal antibodies or an antigen binding portion thereof which bind to prostate specific membrane antigen in its native form occurring on the surface of tumor cells characterized in that it is linked to a label or a cytotoxic agent or constructed as a part of a bispecific antibody or a recombinant diabody.

Anticorps monoclonaux isolés ou partie correspondante de liaison à l'antigène se liant à l'antigène de membrane spécifique à la prostate dans sa forme native à la surface des cellules tumorales, se caractérisant par un lien avec un marqueur ou un agent cytotoxique ou une construction en tant que partie d'anticorps bispécifique ou d'anticorps dimérique (diabody) de recombinaison.

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