Monoclonal antibodies binding human growth hormone (hgh)

Details Monoclonal antibodies binding human growth hormone (hgh) Monoclonal antibodies binding human growth hormone (hgh)

C - Chemistry, Metallurgy

07

K

C07K 16/26 (2006.01) C07K 1/22 (2006.01) C07K 14/61 (2006.01) C12N 5/18 (2006.01) G01N 33/577 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2250047

The invention relates to monoclonal antibody capable of specific binding to the molecular weight of 20 kDa variant of human growth hormone. This monoclonal antibody has no substantial binding to hGH of molecular weight 22 kDa. The invention also relates to the use of this monoclonal antibody for measurement of hGH 20K, especially in body fluids. The antibodies can be used for detection and quantification of hGH 20K, especially in serum.

Cette invention concerne un anticorps monoclonal pouvant se lier spécifiquement à un variant de l'hormone de croissance humaine d'une masse molaire de 20 kDa. Cet anticorps monoclonal ne présente pas de liaison sensible avec l'hormone de croissance humaine ayant une masse molaire de 22 kDa. Cette invention concerne également l'utilisation dudit anticorps monoclonal pour mesurer l'hormone de croissance humaine 20K, tout particulièrement dans les fluides corporels. On peut utiliser ces anticorps pour détecter et quantifier l'hormone de croissance humaine 20K, tout particulièrement dans le sérum.

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