Monoclonal antibodies capable of recognizing...

C - Chemistry – Metallurgy – 12 – P

Patent

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167/37, 195/1.11

C12P 21/08 (2006.01) C07K 16/18 (2006.01) C07K 16/30 (2006.01) C12N 5/18 (2006.01) C12N 5/26 (2006.01) C12N 5/28 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1336763

A hybridoma producing a monoclonal antibody specific to N-acetylneuraminic acid or a derivative thereof in the beta-arrangement as an epitope or antigenic determinant is herein disclosed. The monoclonal antibody produced by the hybridoma can be used in clinical purposes such as diagnosis and/or prognosis of a certain kinds of cancers and acute inflammatory diseases. The hybridoma can be generated by fusing (i) B cells or lymphocytes obtained by immunizing an animal with an N-acetylneuraminic acid or a derivative thereof in beta-arrangement as an antigen and (ii) myeloma cells.

582783

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