Monoclonal antibodies directed against complexes formed by...

C - Chemistry – Metallurgy – 12 – P

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C12P 21/08 (2006.01) C07K 16/36 (2006.01) C07K 16/38 (2006.01) C12N 5/18 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2052501

4-18266/A Monoclonal antibodies directed against complexes formed by thrombin andthrombin inhibitors Abstract of the disclosure The invention concerns monoclonal antibodies which are directed against the thrombin/- hirudin-complex and derivatives thereof, processes for their preparation, hybridoma cell lines secreting said monoclonal antibodies, and processes for the preparation of the hybridoma cell lines. Furthermore, the invention relates to the use of the monoclonal antibodies and/or their derivatives for the determination of the thrombin/hirudin-complex as well as to test kits comprising said monoclonal antibodies and/or their derivatives.

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