Monoclonal antibodies reactive with shared idiotypes on...

Details Monoclonal antibodies reactive with shared idiotypes on... Monoclonal antibodies reactive with shared idiotypes on...

G - Physics

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167/37, 195/1.10

G01N 33/577 (2006.01) A61K 39/395 (2006.01) C07K 16/42 (2006.01) C12N 5/02 (2006.01) G01N 33/564 (2006.01) G01N 33/68 (2006.01)

Patent

CA 1215009

Title MONOCLONAL ANTIBODIES REACTIVE WITH SHARED IDIOTYPES ON HUMAN ANTIBODIES TO NATIVE DNA FROM PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS The invention relates to monoclonal anti-idio- typic antibodies to human anti-DNA antibodies. Mono- clonal, anti-idiotypic antibodies are produced using hybridoma technology. The antibodies ate used as diagnostic reagents in methods to determine the pre- sence of anti-native DNA antibodies in serum from patients suspected of having systemic lupus erythema tosus.

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