Monoclonal antibodies specific for cariogenic bacteria

Details Monoclonal antibodies specific for cariogenic bacteria Monoclonal antibodies specific for cariogenic bacteria

C - Chemistry, Metallurgy

12

P

C12P 21/08 (2006.01) C07K 16/00 (2006.01) C07K 16/12 (2006.01)

Patent

CA 2503347

Antibodies, as well as binding fragments and mimetics thereof, that specifically bind to Actinomyces or Lactobacillus cariogenic bacteria are provided. The subject binding agents, e.g., antibodies, fragments and mimetics thereof, etc., are characterized in that they are highly sensitive and specific for their target bacteria. Also provided are methods and devices for screening samples for the presence of cariogenic bacteria. In addition therapeutic treatment protocols and compositions are provided.

L'invention concerne des anticorps ainsi que des fragments de liaison et des mimétiques de ceux-ci, qui se lient de manière spécifique avec les bactéries Actinomyces ou Lactobacillus cariogènes. Les agents de liaison, p. ex. des anticorps, des fragments et des mimétiques de ceux-ci etc., sont caractérisés en ce qu'ils présentent une sensibilité et une spécificité élevées vis-à-vis de leurs cibles bactériennes. L'invention concerne également des procédés et des dispositifs permettant le criblage d'échantillons en vue d'une détection de bactéries cariogènes. L'invention concerne en outre des protocoles de traitement et des compositions thérapeutiques.

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