Monoclonal antibodies specific for human fibrinopeptide a

Details Monoclonal antibodies specific for human fibrinopeptide a Monoclonal antibodies specific for human fibrinopeptide a

C - Chemistry, Metallurgy

12

N

167/44, 195/1.11

C12N 5/18 (2006.01) C07K 16/36 (2006.01) G01N 33/543 (2006.01) G01N 33/577 (2006.01)

Patent

CA 1338841

The present invention concerns a hybridoma which secretes a monoclonal antibody specific for human A which reacts with free human fibrinopeptide A, but which does not react with intact fibrinogen or human fibrinopeptide A - containing fibrinogen fragments, e.g., the alpha chain of fibrinogen. Such monoclonal antibody can be used in assays to determine the amount of free hFPA in intact plasma.

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