Monoclonal antibodies specific for marrow-derived...

C - Chemistry – Metallurgy – 12 – P

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C12P 21/08 (2006.01) A61F 2/28 (2006.01) A61K 35/28 (2006.01) A61L 27/38 (2006.01) A61L 31/00 (2006.01) C07K 16/28 (2006.01) C12N 5/00 (2006.01) C12N 5/18 (2006.01) G01N 33/554 (2006.01) G01N 33/577 (2006.01) A61F 2/30 (2006.01) A61K 35/12 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2111845

The invention relates to a process for producing monoclonal antibodies which are specific to marrow-derived mesenchymal cells (i.e. mesenchymal stem cells), as well as the monoclonal antibodies that are produced by the process of the invention. In ad- dition, the present invention is directed to the hybrid cell lines or hybridomas that synthesize and secrete these monaspecific an- tibodies, and the use of the monoclonal antibodies for diagnostic and/or therapeutic purposes.

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