Monoclonal antibodies specific for the e2 glycoprotein of...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 16/10 (2006.01) A61K 39/42 (2006.01) C07K 16/42 (2006.01) C12N 15/13 (2006.01) G01N 33/569 (2006.01) G01N 33/576 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2429946

The present invention describes the identification and characterization of five human HC E2-specific monoclonal antibodies isolated form a phage display library and their use in the diagnosis, treatment, and prevention of HCV in mammals, preferably humans.

La présente invention concerne l'identification ainsi que la caractérisation de cinq anticorps monoclonaux humains spécifiques à E2 du VHC isolés d'une banque de présentation de phages ainsi que leurs utilisations dans le diagnostic, le traitement et la prévention du VHC chez des mammifères, de préférence chez l'homme.

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